解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::The interactions between respiration, heart rate and blood pressure variability (HRV, BPV), are considered to be of paramount importance for the study of the functional organisation of the autonomic nervous system (ANS). The aim of the reported study is to detect and classify the intermittent phase locking (PL) phenom...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02345011
更新日期:2000-07-01 00:00:00
abstract::The mechanism of brain contusion has been investigated using a series of three-dimensional (3D) finite element analyses. A head injury model was used to simulate forward and backward rotation around the upper cervical vertebra. Intracranial pressure and shear stress responses were calculated and compared. The results ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02347044
更新日期:2000-05-01 00:00:00
abstract::Bone mass and microarchitecture are the main determinants of bone strength. Three-dimensional micro-computed tomography has the potential to examine complete bones of small laboratory animals with very high resolution in a non-invasive way. In the presented work, the proximal part of the tibiae of hindlimb unloaded an...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02347054
更新日期:2000-05-01 00:00:00
abstract::A process is described for the fabrication of silicon-based microelectrodes for neurophysiology using bonded and etched-back silicon-on-insulator (BESOI) wafers. The probe shapes are defined without high levels of boron doping in the silicon; this is considered as a step towards producing probes with active electronic...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02344773
更新日期:2000-03-01 00:00:00
abstract::Thousands of patients receive human tissue grafts every year. Developments in cell and tissue engineering have also increased considerably the number of available products of human origin. France has very strict regulations, in part stimulated by problems of public health and ethics that have emerged in recent years a...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02344783
更新日期:2000-03-01 00:00:00
abstract::An algorithm for determining the frequency and propagation time of the gastric slow wave has been designed for integration into a demand gastric pacing system. The algorithm analyses the serosal activity in both the time and frequency domains, and the results are compared to produce a conclusion only when the values a...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02344688
更新日期:2000-01-01 00:00:00
abstract::Neural networks are trained to estimate the germination percentages of Plasmopara viticola oospores, overwintered in natural conditions in two viticultural areas in northern Italy, by using climatic (temperature and rainfall) data, as well as the previous germination measurement, as input variables. The 288 available ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02344698
更新日期:2000-01-01 00:00:00
abstract::An original numerical method is developed to compute the 3D electric potential generated by a dot-contact cuff electrode implanted around an axisymmetrical, inhomogeneous, anisotropic nerve. The technique is based on a 2D finite-element approach coupled with a semi-analytical Fourier spectral decomposition to approxim...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02513375
更新日期:1999-11-01 00:00:00
abstract::Magnetoenterography (MENG) is a new, non-invasive technique that measures gastrointestinal magnetic signals near the body surface. This study was undertaken to evaluate the temporal and spatial characteristics of the magnetic signals generated by gastric and duodenal slow wave activity. The gastrointestinal magnetic f...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02513347
更新日期:1999-09-01 00:00:00
abstract::Tissue hardness is related to tissue composition, and this is often changed by disease. It is therefore of interest to measure the hardness in an objective and non-invasive way. A tactile sensor based on a vibrating piezoelectric ceramic element in a feedback loop is described. When the sensor touches an object it pro...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02513357
更新日期:1999-09-01 00:00:00
abstract::During scoliosis instrumentation surgery, it is difficult for surgeons fully to track vertebral motion in 3D, because only the posterior elements of the spine are exposed. Different intra-operative modelling approaches are evaluated using a registration technique that matches intra-operative measurements with a 3D pre...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02513328
更新日期:1999-07-01 00:00:00
abstract::Both invasive left-ventricular pressure measurements and non-invasive colour M-mode echographic measurements have shown the existence of intraventricular pressure gradients (IVPGs) during early filling. The mechanisms responsible for these IVPG cannot be completely explained by the experiments. Therefore a one-dimensi...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02513338
更新日期:1999-07-01 00:00:00
abstract::A method for the estimation of medium rate transitions of non-stationary electroencephalograms (EEG) is proposed. The method is applicable to such EEG dynamics that are between (a) fast transitions for which segmentation procedures are used and (b) slow transitions for which adaptive filters work properly. The estimat...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02513305
更新日期:1999-05-01 00:00:00
abstract::An automatic power-generating system (AGS) which converts kinetic energy into electric energy for quartz watches was tested as a power source for implantable cardiac pacemakers. An automatic power-generating mechanism and a capacitor (0.33 F) were removed from a quartz watch (SEIKO) and encapsulated in a polyvinyl cas...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02513315
更新日期:1999-05-01 00:00:00
abstract::Left ventricular volume calibration based on the conductance catheter depends on the correct determination of the parallel conductance (Gp). Baan's saline manoeuvre procedure leads to Gp by finding the end-systolic (Ges) and end-diastolic (Ged) conductances, for each beat of the dilution curve rising limb. After plott...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02513284
更新日期:1999-03-01 00:00:00
abstract::The passive and active properties of the cochlear outer hair cell are studied. The outer hair cell is currently considered the major candidate for the active component of mammalian hearing. Understanding of its properties may explain the amplification and sharp frequency selectivity of the ear. To analyse the cell beh...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02513294
更新日期:1999-03-01 00:00:00
abstract::To evaluate the possibility of respiratory-volume measurement using photoplethysmography (PPG), PPG signals from 16 normal volunteers are collected, and the respiratory-induced intensity variations (RIIV) are digitally extracted. The RIIV signals are studied while respiratory volume is varied. Furthermore, respiratory...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02513264
更新日期:1999-01-01 00:00:00
abstract::The paper describes the application of new semi-automatic segmentation software to the task of detection of anatomical structures and lesion and their three-dimensional (3D) visualisation in 23 patients with secondary progressive multiple sclerosis (MS). The purpose is to study the correlation between magnetic resonan...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02513274
更新日期:1999-01-01 00:00:00
abstract::A system composed of a functional continuous magnetic stimulator (FCMS) and a saddle-type coil has been developed for non-invasive treatment of urinary incontinence, especially stress incontinence and urge incontinence. The FCMS conditions were as follows: 2 kW maximum electrical power consumption, 800 V maximum capac...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02518872
更新日期:1998-11-01 00:00:00
abstract::In a computerised ultrasound image guidance for automated prostatectomy system, it is necessary to identify a smooth, continuous contour for the prostate (boundary) from the ultrasound image. The radial bas-relief (RBR) method, which has been reported previously, can extract a skeletonised image from an ultrasound ima...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02518882
更新日期:1998-11-01 00:00:00
abstract::Spectral analysis of heart rate variability (HRV) is an accepted method for assessment of cardiac autonomic function and its relationship to numerous disorders and diseases. Various non-parametric methods for HRV estimation have been developed. The spectrum of counts, the instantaneous heart rate spectrum and the inte...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02524426
更新日期:1998-09-01 00:00:00
abstract::Sealing resistance is highly significant with respect to the electrical neuron-electrode contact because it decreases the stimulation threshold of neurons cultured on a planar micro-electrode array. A method is proposed for measurement of the sealing resistance using impedance spectroscopy. The effect of the sealing r...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02524436
更新日期:1998-09-01 00:00:00
abstract::A strict EIT reconstruction algorithm, the general inversion algorithm (GIA) is presented. To improve the noise performance, the algorithm is modified by attenuating the condition number of the forward matrix F and implemented using an improved FEM scheme, to obtain the 2D image of impedance change (dynamic image). Th...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02523205
更新日期:1998-07-01 00:00:00
abstract::Haematocrit and temperature effects on resistivity are investigated using the electrical impedance method. Measurements are made extensively for pig's blood. The experimental set-up basically involves four ring electrodes being placed around a wooden probe that is subsequently immersed into a syringe containing pig's ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02523215
更新日期:1998-07-01 00:00:00
abstract::The three-dimensional changes in the cytoskeleton and in cell proliferation of bovine pulmonary artery endothelial cells when exposed to sustained hydrostatic pressure were investigated in vitro using laser scanning confocal microscopy. Subconfluent endothelial cells on rigid substrates were exposed to 1.5, 5 and 10 c...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02523225
更新日期:1998-07-01 00:00:00
abstract::The study focuses on the problems of dimensionality reduction by means of principal component analysis (PCA) in the context of single-trial EEG data classification (i.e. discriminating between imagined left- and right-hand movement). The principal components with the highest variance, however, do not necessarily carry...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02522476
更新日期:1998-05-01 00:00:00
abstract::Neurofilaments are organised into parallel bundles in axons through crossbridges formed by lateral projections of neurofilament subunits. Pure neurofilaments form gels in vitro, consisting of interconnected parallel arrays of filaments regulated by the phosphorylation level of neurofilament subunits. Neurofilament-ass...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02522486
更新日期:1998-05-01 00:00:00
abstract::Visual inspection of foetal heart rate (FHR) sequences is an important means of foetal well-being evaluation. The application of fractal features for classifying physiologically relevant FHR sequence patterns is reported. The use of fractal features is motivated by the difficulties exhibited by traditional classificat...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02510743
更新日期:1998-03-01 00:00:00
abstract::A three-layer Newtonian model is investigated using a combined Eulerian-Lagrangian computational method to describe the dynamic behaviour of leukocytes. The model, composed of a cell membrane (outer layer), cytoplasm (middle layer) and nucleus (inner layer), can better describe the recovery characteristics because lar...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02510753
更新日期:1998-03-01 00:00:00
abstract::The aim of this study was to develop a radiation-free method to measure gastric emptying. Such a method would be useful e.g. for patients who need repeated measurements and in pregnancy. Ferrimagnetic particles (gamma-Fe2O3), ingested within a solid test meal (pancakes), were magnetised by an applied magnetic field. A...
journal_title:Medical & biological engineering & computing
pub_type: 临床试验,杂志文章
doi:10.1007/BF02522849
更新日期:1998-01-01 00:00:00
abstract::The aim of the study is to establish the validity of the use of the electrical impedance technique for estimating local oedema in extremities through comparison with computed-tomography (CT) analysis. Eight healthy women (group 1) and nine women with unilateral leg oedema following chronic lymphatic obstruction (group...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02522859
更新日期:1998-01-01 00:00:00
abstract::The effect of flow direction on the morphology of cultured bovine aortic endothelial cells is studied. Fully confluent endothelial cells cultured on glass were subjected to a fluid-imposed shear stress of 2 Pa for 20 min and 24 h using a parallel plate flow chamber. Experiments on shear flow exposure were performed fo...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02522869
更新日期:1998-01-01 00:00:00
abstract::Transurethral resection of the prostate is the most common method of relieving urinary outflow obstruction secondary to prostatic enlargement. However, this procedure can be responsible for various complications, including irrigant-fluid absorption and blood loss, both of which are strongly dependent on operation dura...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02510962
更新日期:1997-11-01 00:00:00
abstract::To describe upper airway obstruction in patients with sleep apnea syndrome, the steady state solutions of a simple model of local pharyngeal obstruction were studied. Importantly, the present model embodies a series of two individualised elements, each having its own compliance, which enables the consideration, from a...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02510972
更新日期:1997-11-01 00:00:00
abstract::On the basis of spatial covariance it is found that, by spatial filtering the localisation of a single dipole source, both parallel and perpendicular to the measurement plane (assuming a signal-noise ratio of 5:1), can be performed with an accuracy of < 0.5 mm. When the signal-noise ratio is increased to 30:1, the res...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02510982
更新日期:1997-11-01 00:00:00
abstract::The object of this study is to compare the performance of two new bilinear time-frequency representation techniques with the spectrogram to characterise the behaviour of heart murmurs produced by bioprosthetic heart valves implanted in the mitral or aortic position. The murmurs are those of mitral stenosis, mitral reg...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02525526
更新日期:1997-09-01 00:00:00
abstract::The complexity of the monitored data available in modern intensive care units suggests that they may be best processed, for presentation to medical staff, by expert system techniques. However, standard expert system shells are ill-fitted to either the basic sequential monitoring tasks of data acquisition and storage, ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02525536
更新日期:1997-09-01 00:00:00
abstract::Electrical and mechanical stimulation of the oesophagus has been recently proposed to examine the physiological effects of autonomic stimulation in humans. Cortical evoked potentials (EPs) to oesophageal stimulation provide an assessment of afferent fibres and central processing. However, habituation takes place durin...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02534088
更新日期:1997-07-01 00:00:00
abstract::A multichannel biopotential amplifier for simultaneous use with biomagnetic measurements in a magnetically shielded room is designed and evaluated. Particular care is taken to make the amplifier electromagnetically compatible with the biomagnetic instruments over the whole frequency spectrum, from DC to RF. The electr...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02534098
更新日期:1997-07-01 00:00:00
abstract::In acute experiments the sciatic nerve of the rat is electrically stimulated to induce fatigue in the medial Gastrocnemius muscle. Fatigue tests are carried out using intermittent stimulation of different compartments (sequential) or a single compartment (synchronous) of the sciatic nerve. The activation of different ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02530036
更新日期:1997-05-01 00:00:00